This is a slide that I have used in some of my presentations. If you look at the citations for epilepsy, autism and schizophrenia in Nature, Science and Nature Genetics, you will see this pattern: The run of papers in 2000-2001 corresponding to the era of the monogenic epilepsies and the 2007-2009 era, when papers on schizophrenia and autism overtake the publications on epilepsy. The 2007-2009 peak for autism and schizophrenia is mainly due to the identification of rare CNVs in these disorders, a research strategy that has only been applied to the epilepsies more recently.
This widening gap between autism, schizophrenia research and epilepsy research is the Cinderella phenomenon as a reference to a statement by William G. Lennox:
“Epilepsy is no longer the Cinderella of medicine. The electroencephalograph is her glass slipper.” William G. Lennox, 1947
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